Combined Injury: Radiation with Other Injuries

Uniformed Services University

Combined Injury: Radiation with Other Injuries

After a nuclear detonation, a high percentage of radiation casualties will have combined injuries: radiation exposure combined with wounds, burns or other trauma. Research at AFRRI and elsewhere has shown a powerful synergy between radiation and other injuries in causing deleterious biological effects, including enhanced ARS, delayed wound healing and increased mortality. Pharmacological countermeasures that are effective against radiation injury alone are not always effective against combined injury. AFRRI is discovering mechanisms of, and developing promising candidates for combined injury.