Anesthesiology Faculty
Anesthesiology
ANE Contact Info
Chair (301) 295-3140
Fax (301) 295-2200
ANE - Local/NCA Faculty
Eric Holt, Colonel, Air Force
Name: Eric Holt, Colonel, Air Force
USU Department of Primary Appointment:
Anesthesiology
Title:
Vice-Chairman
Faculty Rank:
Assistant Professor
Location:
Uniformed Services University of the Health Sciences, Bethesda, MD
Email:
Education
Chronic Pain Fellowship
WRNMMCB
Bethesda MD
(2012 -- 2013)
Master of Strategic Studies
Air War College
Montgomery AL
(2009-2013)
Anesthesiology Residency
Harvard University BIDMC
Boston MA
(2002 -- 2005)
Transitional Internship
Midwestern University -SJOFMC
Olympia Fields IL
(2001 -- 2002)
Osteopathic Doctorate
Midwestern University
Downers Grove IL
(1997 -- 2001)
Masters of Business Administration
Western New England College
Springfield MA
(1995 -- 1997)
Bachelor of Science
United States Military Academy
West Point NY
(1987 -- 1991)
WRNMMCB
Bethesda MD
(2012 -- 2013)
Master of Strategic Studies
Air War College
Montgomery AL
(2009-2013)
Anesthesiology Residency
Harvard University BIDMC
Boston MA
(2002 -- 2005)
Transitional Internship
Midwestern University -SJOFMC
Olympia Fields IL
(2001 -- 2002)
Osteopathic Doctorate
Midwestern University
Downers Grove IL
(1997 -- 2001)
Masters of Business Administration
Western New England College
Springfield MA
(1995 -- 1997)
Bachelor of Science
United States Military Academy
West Point NY
(1987 -- 1991)
Bibliography
- Vice-Chairman USUHS Department of Anesthesiology
- Clerkship Director USUHS Department of Anesthesiology
- Multiple deployments
- Awards and Decorations available upon request
Luke Michaelson, PhD, RN
Name: Luke Michaelson, PhD, RN
USU Department of Primary Appointment:
Anesthesiology
Title:
Research Assistant Professor
Faculty Rank:
Assistant Professor
Location:
Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Malignant Hyperthermia
Calcium kinetics, muscle physiology, embedded heavy metals
Email:
Office Phone:
(301) 295-3142
Department Website:
Education
2011 Doctor of Philosophy, Nursing University of Maryland School of Nursing, Baltimore, MD
2007 Master of Science, Nursing: Clinical Research Management University of Maryland School of Nursing, Baltimore, MD
2003 Bachelor of Science, Nursing University of Maryland School of Nursing, Baltimore, MD
1996 Bachelor of Science, Chemical Engineering Florida Institute of Technology Melbourne, FL
2007 Master of Science, Nursing: Clinical Research Management University of Maryland School of Nursing, Baltimore, MD
2003 Bachelor of Science, Nursing University of Maryland School of Nursing, Baltimore, MD
1996 Bachelor of Science, Chemical Engineering Florida Institute of Technology Melbourne, FL
Biography
Dr. Michaelson was commissioned as a Second Lieutenant in the Ordnance Corps (Reserves), Army, from ROTC. He graduated with a Bachelor’s of Science degree in Chemical Engineering in 1996 from Florida Institute of Technology. Dr. Michaelson then accepted positions within the 536th Support Battalion (Forward) Texas Army Reserve National Guard as a Supply Officer and Maintenance Control Officer. His concurrent civilian work at Bechtel International included Subcontract and Contract Administrator responsibilities (1997-2001). Dr. Michaelson then changed careers and graduated from the University of Maryland School of Nursing with a BSN in 2004. After graduation, he worked as an Emergency Department and Chest Pain Unit staff nurse at Howard County General Hospital, in Columbia, MD for approximately three years.
Dr. Michaelson continued his education and completed his Doctor of Philosophy in Nursing (2011) focusing on the altered calcium homeostasis in dystrophic skeletal muscle at the University of Maryland. The Department of Veterans Affairs then awarded Dr. Michaelson a Postdoctoral Nursing Fellowship (2012-2015) in Dr. Christine E. Kasper’s Lab at the Uniformed Services University. His postdoctoral research investigated how implanted heavy metals altered the fatigability and susceptibility of eccentric injury in skeletal muscle. Dr. Michaelson accepted a Research Assistant Professor position within the Department of Anesthesiology in 2016. He currently performs the diagnostic caffeine halothane contracture test (CHCT) for the Malignant Hyperthermia Diagnostic Laboratory for military and civilian subjects. His research now investigates calcium homeostasis differences between malignant hyperthermia susceptible (MHS) and malignant hyperthermia non-susceptible (MHN) subjects using a B-lymphocyte model.
Extramural/ Intramural Funding
2015 - 2020 $2.5 million
“An Interdisciplinary Approach to Investigating Exertional Related Injuries in the Service Member.”
Program Project Grant, ANE-80-3397, Project 3, Biomarkers for ERI
CAPT Dale Szpisjak (PI) Luke Michaelson (Co-PI).
2014 – 2017 $71,178
“CNG Channel Expression and cAMP Levels in Human B-Cells: A Pilot Study,”
Department of Veterans Affairs Office of Nursing Services Pilot Study Award
Luke Michaelson (PI), Sheila Muldoon (Co-PI), Colonel Susan Perry (Co-PI), Christine Kasper (Co-PI)
2013 – 2014 $75,000
“Pilot Study of Fatigability, and Eccentric Injury Comparison Between Skeletal Muscle of Heavy Metal (Tungsten, Nickel/Cobalt) Imbedded F344 Rats and Non-Heavy Metal Imbedded Rats,”
Department of Veterans Affairs Office of Nursing Services Pilot Study
Luke Michaelson (PI), Christine Kasper (Co-PI)
2009 - 2011 $83,375
Stress Induced Ca 2+ Dysregulation in MDX Mouse Skeletal Muscle Fibers
Ruth L. Kirschstein National Research Service Award (NRSA) for Individual Predoctoral Fellows (F31) in Nursing Research
1F31NR011245-01
Luke Michaelson (PI), Christopher Ward (PhD Advisor)
2010 - 2011 $3,500/yr
Foundation of the National Student Nurses’ Association, Inc.
Promise of Nursing Regional Faculty Fellowship Program
Luke Michaelson (PI), Christopher Ward (PhD Advisor)
2007 – 2009 $30,000/yr
Department of Health and Human Services Public Health Services Interdisciplinary Training Program in Muscle Biology
(T32) AR007592
Luke Michaelson (Research Assistant)
2006 – 2009 $35,000/yr
Department of Education: Graduate Assistance in Areas of National Need (GAANN) Fellowship
Luke Michaelson (Fellow)
Recent Presentations
September, 2017
Malignant Hyperthermia Association of the United States
RyR1 Pathogenic Variant in an Unpublished Malignant Hyperthermia Case From 1984
Michaelson, L.P., Sambuughin, N.,Voelkel, M., Muldoon, S.M., Szpisjak, D.F.
September, 2017
Malignant Hyperthermia Association of the United States
Comparing Malignant Hyperthermia and Exertional Rhabdomyolysis/Heat Illness: A CHCT and RYR1 Analysis
O. Mungunsukh, O., Michaelson, L.P., Sambuughin, N., Muldoon, S.M., Deuster, P., Voelkel, M., Szpisjak, D.F., O’Connor, F.G., Capacchione, J.F.
April, 2017
Experimental Biology 2017
Recovery from Fatigue and Injury in Rat Muscle Embedded with Heavy Metals
Michaelson, L. P., Lovering, R.M., Tossini, N., Kasper, C.E.
May, 2015
Uniformed Services University of the Health Sciences Research Day
Comparison of Skeletal Muscle Eccentric Injury in F344 Rats Embedded With and Without Tungsten Alloy (Tungsten, Nickel, Cobalt)
Michaelson, L., Pratt, S., Lovering, R., Ward, C.W., Kasper, C.E.,
October, 2014
Greater District of Columbia American Physiological Society Meeting
Evaluation of the Cyclic Nucleotide Gated Channel in Human B-lymphocytes From Malignant Hyperthermia Susceptible and Malignant Hyperthermia Non-Susceptible Persons
Michaelson, L., Muldoon, S., Perry, S., Sambuughin N., Kasper, C.E.
Teaching
Uniformed Services University of the Health Sciences
Graduate Courses
2016 Malignant Hyperthermia section in RNA 602 Applied Biochemistry for Nurse Anesthetists
2014 Immunology section in GSN 603 Advanced Physiology
2013 Muscle Physiology section in GSN 603 Advanced Physiology
2013 Quantitative Data section in PHD 813 Theoretical Models
University of Maryland School of Nursing
Undergraduate Courses:
2011 - 2013 Renal Physiology and Pathophysiology; Alterations in Fluid and Electrolyte Balance sections in NUR 315 Pathopharmacology
Graduate Courses
2012 - 2013 Membrane Signaling and Special Lipids sections in NUR 616 Biochemistry for Nurse Anesthesia
Dr. Michaelson continued his education and completed his Doctor of Philosophy in Nursing (2011) focusing on the altered calcium homeostasis in dystrophic skeletal muscle at the University of Maryland. The Department of Veterans Affairs then awarded Dr. Michaelson a Postdoctoral Nursing Fellowship (2012-2015) in Dr. Christine E. Kasper’s Lab at the Uniformed Services University. His postdoctoral research investigated how implanted heavy metals altered the fatigability and susceptibility of eccentric injury in skeletal muscle. Dr. Michaelson accepted a Research Assistant Professor position within the Department of Anesthesiology in 2016. He currently performs the diagnostic caffeine halothane contracture test (CHCT) for the Malignant Hyperthermia Diagnostic Laboratory for military and civilian subjects. His research now investigates calcium homeostasis differences between malignant hyperthermia susceptible (MHS) and malignant hyperthermia non-susceptible (MHN) subjects using a B-lymphocyte model.
Extramural/ Intramural Funding
2015 - 2020 $2.5 million
“An Interdisciplinary Approach to Investigating Exertional Related Injuries in the Service Member.”
Program Project Grant, ANE-80-3397, Project 3, Biomarkers for ERI
CAPT Dale Szpisjak (PI) Luke Michaelson (Co-PI).
2014 – 2017 $71,178
“CNG Channel Expression and cAMP Levels in Human B-Cells: A Pilot Study,”
Department of Veterans Affairs Office of Nursing Services Pilot Study Award
Luke Michaelson (PI), Sheila Muldoon (Co-PI), Colonel Susan Perry (Co-PI), Christine Kasper (Co-PI)
2013 – 2014 $75,000
“Pilot Study of Fatigability, and Eccentric Injury Comparison Between Skeletal Muscle of Heavy Metal (Tungsten, Nickel/Cobalt) Imbedded F344 Rats and Non-Heavy Metal Imbedded Rats,”
Department of Veterans Affairs Office of Nursing Services Pilot Study
Luke Michaelson (PI), Christine Kasper (Co-PI)
2009 - 2011 $83,375
Stress Induced Ca 2+ Dysregulation in MDX Mouse Skeletal Muscle Fibers
Ruth L. Kirschstein National Research Service Award (NRSA) for Individual Predoctoral Fellows (F31) in Nursing Research
1F31NR011245-01
Luke Michaelson (PI), Christopher Ward (PhD Advisor)
2010 - 2011 $3,500/yr
Foundation of the National Student Nurses’ Association, Inc.
Promise of Nursing Regional Faculty Fellowship Program
Luke Michaelson (PI), Christopher Ward (PhD Advisor)
2007 – 2009 $30,000/yr
Department of Health and Human Services Public Health Services Interdisciplinary Training Program in Muscle Biology
(T32) AR007592
Luke Michaelson (Research Assistant)
2006 – 2009 $35,000/yr
Department of Education: Graduate Assistance in Areas of National Need (GAANN) Fellowship
Luke Michaelson (Fellow)
Recent Presentations
September, 2017
Malignant Hyperthermia Association of the United States
RyR1 Pathogenic Variant in an Unpublished Malignant Hyperthermia Case From 1984
Michaelson, L.P., Sambuughin, N.,Voelkel, M., Muldoon, S.M., Szpisjak, D.F.
September, 2017
Malignant Hyperthermia Association of the United States
Comparing Malignant Hyperthermia and Exertional Rhabdomyolysis/Heat Illness: A CHCT and RYR1 Analysis
O. Mungunsukh, O., Michaelson, L.P., Sambuughin, N., Muldoon, S.M., Deuster, P., Voelkel, M., Szpisjak, D.F., O’Connor, F.G., Capacchione, J.F.
April, 2017
Experimental Biology 2017
Recovery from Fatigue and Injury in Rat Muscle Embedded with Heavy Metals
Michaelson, L. P., Lovering, R.M., Tossini, N., Kasper, C.E.
May, 2015
Uniformed Services University of the Health Sciences Research Day
Comparison of Skeletal Muscle Eccentric Injury in F344 Rats Embedded With and Without Tungsten Alloy (Tungsten, Nickel, Cobalt)
Michaelson, L., Pratt, S., Lovering, R., Ward, C.W., Kasper, C.E.,
October, 2014
Greater District of Columbia American Physiological Society Meeting
Evaluation of the Cyclic Nucleotide Gated Channel in Human B-lymphocytes From Malignant Hyperthermia Susceptible and Malignant Hyperthermia Non-Susceptible Persons
Michaelson, L., Muldoon, S., Perry, S., Sambuughin N., Kasper, C.E.
Teaching
Uniformed Services University of the Health Sciences
Graduate Courses
2016 Malignant Hyperthermia section in RNA 602 Applied Biochemistry for Nurse Anesthetists
2014 Immunology section in GSN 603 Advanced Physiology
2013 Muscle Physiology section in GSN 603 Advanced Physiology
2013 Quantitative Data section in PHD 813 Theoretical Models
University of Maryland School of Nursing
Undergraduate Courses:
2011 - 2013 Renal Physiology and Pathophysiology; Alterations in Fluid and Electrolyte Balance sections in NUR 315 Pathopharmacology
Graduate Courses
2012 - 2013 Membrane Signaling and Special Lipids sections in NUR 616 Biochemistry for Nurse Anesthesia
Representative publications, projects, and/or deployments
- American Association for the Advancement of Science - Member
- The American Physiological Society - Member
- Biophysical Society - Member
- Maryland Nurses Association - Legislative Committee Member
- Maryland Nurses Association - Environmental Health Committee (Chairperson)
- Adjunct Faculty - University of Maryland School of Nursing
- Adjunct Member - Department of Veterans Affairs
Bibliography
- Perry, S., Michaelson, L., Bunger, R., Muldoon, S., Kasper, C.E. (accepted for publication) The Effect of Norepinephrine on Intracellular Ca2+ levels in MHS B Cells: Pilot Study in the Search for a New Diagnostic Test for MH. American Association of Nurse Anesthetists Journal.
- Michaelson, L., Ward, C., Iler, Colleen. (2013) ROS and RNS signaling in skeletal muscle: critical signals and therapeutic targets. Annual Review of Nursing Research 31(1), 367-387.
- Michaelson, L., & Russ, K. (2013). Nurses' Voice and Fracking in Maryland. The Maryland Nurse News and Journal, 14(2), 3-4.
- Michaelson, L.P., Shi, G., Ward, C.W., Rodney G.G., (2010). Mitochondrial redox potential during contraction in single intact muscle fibers. Muscle & Nerve. 42(4), 522-529.
- Lovering, R.M., Michaelson, L., Ward, C.W., (2009). Malformed mdx myofibers have normal cytoskeletal architecture yet altered EC Coupling and stress-induced Ca2+. American Journal of Physiology – Cell Physiology. 297, 571-580.
- Cherednichenko, G., Ward, C., Feng, W., Cabrales, E., Michaelson, L., Samso, M., Lopez, J., Allen, P.D., Pessah, I.N., (2008) Enhanced Excitation-Coupled Calcium Entry (ECCE) in Myotubes Expressing Malignant Hyperthermia Mutation R163C is Attenuated by Dantrolene. Molecular Pharmacology. 73(4), 1203-1212.
Dale F Szpisjak, MD, MPH, Captain, Navy
Name: Dale F Szpisjak, MD, MPH, Captain, Navy
USU Department of Primary Appointment:
Anesthesiology
Title:
Chair, Department of Anesthesiology
Faculty Rank:
Associate Professor
Location:
Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Field Anesthesia Machines
Malignant Hyperthermia
Email:
Office Phone:
(301) 295-3140
Department Website:
Education
1987 BS United States Naval Academy, Annapolis, MD
1991 MD Southern Illinois University School of Medicine, Springfield, IL
1992 Medicine Intern Naval Hospital, Oakland, CA
1995 Anesthesiology Resident University of California, San Francisco, CA
1998 Pediatric Anesthesiology Fellowship Hospital for Sick Children, University of Toronto, Ontario, Canada
2007 MPH Uniformed Services University, Bethesda, MD
1991 MD Southern Illinois University School of Medicine, Springfield, IL
1992 Medicine Intern Naval Hospital, Oakland, CA
1995 Anesthesiology Resident University of California, San Francisco, CA
1998 Pediatric Anesthesiology Fellowship Hospital for Sick Children, University of Toronto, Ontario, Canada
2007 MPH Uniformed Services University, Bethesda, MD
Representative publications, projects, and/or deployments
- 1. Szpisjak DF, Edgell DS, Bissonnette B. Potassium as a surrogate marker of debris in cell- salvaged blood. Anesth Analg 2000;91:40-3.
- 2. Szpisjak DF. Debris elimination from partially-filled cell salvage bowls. Anesth Analg 2001;92:1137-8.
- 3. Szpisjak DF, Potter PS, Capehart BP. Economic Analysis of an Intraoperative Cell-Salvage Service. Anesth Analg 2004:98:201-5.
- 4. Serianni RP, Shields CH, Szpisjak DF, Mongan PD. Intraoperative management: peripheral vascular surgery. Anesthesiol Clin North America 2004;22:307-18.
- 5. Szpisjak DF, Lamb CL, Klions KD. Oxygen Consumption with Mechanical Ventilation in a Field Anesthesia Machine. Anesth Analg 2005;100:1713-17.
- 6. Szpisjak DF, Javernick EN, Kyle RR, Austin PN. Drive gas volume of a pneumatically powered and controlled field anesthesia machine ventilator. Anesth Analg 2008;107: 1907-1911.
- 7. Keneally R, Szpisjak DF, et al. Thoracic trauma in Iraq and Afghanistan. J Trauma Acute Care Surg. 2013 May;74(5):1292-7.
- 8. Szpisjak DF, Starrett-Keller CM. Field anesthesia machine ventilator oxygen consumption in models of high and low pulmonary compliance. Mil Med 2014;179:1465-8.
- 9. Hudson AJ, Whittaker DR, Szpisjak DF, et al. Tumescent technique without epinephrine for endovenous laser therapy and serum lidocaine concentration. J Vasc Surg: Venous and Lym Dis 2015;3:48-53.
- 10. Szpisjak DF, Giberman AA. Air compressor battery duration with mechanical ventilation in a field anesthesia machine. Mil Med 2015;180:499-502.
Bibliography
- 11. Hudson AJ, Whittaker DR, Szpisjak DF, et al. Reply. J Vasc Surg: Venous and Lym Dis 2015;3:345.
- 12. Szpisjak DF, Horn G, Shalov S, Abes AA, Van Decar L. Minute ventilation limitations of two field transport ventilators. Mil Med 2017;182:e1653-e1657.
- 13. Keneally RJ, Szpisjak DF, Hoffman P, Park E, Albergo M. Vital signs and physiologic derangement in patients with thoracic trauma in Iraq and Afghanistan. Mil Med 2017;182:e1881-e1884.
- 14. Hudson AJ, Walter RJ, Flynn J, Szpisjak DF, et al. Ambulatory Surgery has minimal impact on sleep parameters: a prospective observational trial. J Clin Sleep Med; In Press.
