CHIRP Research

CHIRP

Our Facility

CHIRP is located at 4301 Jones Bridge Road, Bethesda, MD, 20814, on the campus of the Walter Reed National Military Medical Center (WRNMMC). CHIRP is served by the Medical Center Metro stop (Red Line).

Research

The following investigators were awarded in the first phase of the RFA.

 

Principal Investigator

Title

Co-Principal Investigators

Department

Sub Program

RFA-1/2

Biswas, Roopa

Epigenetic regulation of F508del-CFTR cystic fibrosis lung disease

FRIZZELL, RAYMOND A (University of Pittsburgh School ofMedicine)/GOROSPE, MYRIAM (NIH National Institute on Aging)/Olsen, Cara (USUHS)

Clinical

Lung diseases and Conditions

RFA-2

Buckenmaier, Chester

Biomarker signatures of the sleep-pain enigma

Knollman-Ritschel, Barbara (USU/HJF)/Bhomia, Manish (USU)/Dickens, Jonathan F (WRNMMC)/ Highland, Krista Beth (HJF)/Kent, Michael (USU)/ Mauntel, Timothy (WRNMMC)

Clinical

Sleep disorders

RFA-2

Cox,Rachel

Identifying mitochondrial proteinaceous RNAse P mutations linked to hypertension

Koutmos Ph.D., Markos, USUHS

Biochemistry

Heart and Vascular Disease

RFA-1

Dalgard, Clifton L

Defining genetic etiology of inflammatory vasculopathy in Mendalian autoinflammatory syndromes and their role in common complex vascular disease

Boehm, Manfred (NHLBI)/Brofferio, Alessandra (NHLBI)/Goldbach-Mansky, Raphaela T (NIAID)/ Jones, Olay (WRNMMC)

Clinical

Heart and Vascular Disease

RFA-2

Darling, Thomas

Genomics of Lymphangioleiomyomatosis and Tuberous Sclerosis Complex

Moss, Joel, NHLBI,Thangapazham, Rajesh/ Klover, Peter/Li, Shaowei

Dermatology

Lung Diseases and Conditions

RFA-1

DUNN, TERESA M

The Impact of ORMDL3 Expression on T Lymphocyte Activation and Asthma Pathogenesis

Snow, Andrew L (HJF)/Holley, Aaron (San Antonio Military Medical Center)/Proia, Richard (NIH/NIDDK)Mitre, Edward (USU)

Clinical

Lung diseases and Conditions

RFA-2

Dveksler,Gabriela

Expression of pregnancy-specific glycoproteins in preeclampsia

Austin, Melissa, WRNMMC

Pathology

Heart and Vascular Disease

RFA-1

Flagg, Thomas

Metabolism, Epigenetics and Hypertrophic Cardiomyopathy

Haigney, Mark Charles, USU

APG

Heart and Vascular Disease

RFA-1

Galdzicki,Zygmunt

Sleep Deficits and Physiological Stress in High Altitude Conditions

Cramer, Nathan/Snow, Andrew /Tankersley, Clarke G/Vgontzas, Alexandros N (Penn State Univ./Dalgard, Clifton/Rapoport, Stanley (NIA)/ Heller, Craig H (Stanford Univ.)

APG

Sleep Disorders

RFA-1

HAIGNEY, MARK Charles

Genetic Contributions to Sudden Cardiac Arrest in the Military.

Dalgard, Clifton (USU)/FLAGG, THOMAS (USU)/ Hellwig, Lydia (USU)/KLEIN, MICHAEL G (USU)/ Manolio, Teri (USU)/Needleman, Matthew (USU)/ Sack, Michael N (USU)/Turner, Clesson (USU)/ Wilkerson, Matthew Devin (USU)

Clinical

Heart and Vascular Disease

RFA-2

Namboodiri, Ma

Acetate Supplementation using Glyceryl Triacetate as an Adjunct Therapy for Hemorrhagic Shock and Injury

Elster, Eric A, USU/Flagg, Thomas/Moffett, John R/DAvis, Thomas/Arun, Peetheambaran

APG

Blood Diseases and Conditions

RFA-1

Pratt, Kathleen

Hemophilia A and Immune Responses to Factor VIII

Newton, Thomas Charles, WRNMMC/Wilkerson, Matthew /Dalgard, Clifton

Medicine

Blood Diseases and Conditions

RFA-1

Quinnan,Gerald

Metagenomic Analysis of Respiratory Samples from Patients with Acute Respiratory Infection

Bishop-Lilly, Kimberly A, Naval Medical Research Center/Coles, Christian/Stewart, Dr. Ann V/ Zhang, Dr. Pengfei

Preventive Med. & Biometrics

Lung Diseases and Conditions

RFA-1

Smyth, Jeremy Thomas

Role of Stim and Orai calcium signaling proteins in heart development and pathological cardiac hypertrophy

Hammer, John A (NHLBI)

Basic

Heart and Vascular Disease

RFA-2

Tan,Shyh-Han

Genomic Landscape of the Sickle Cell Trait Associated Lethal Kidney Cancer

Petrovics,Gyorgy, USU;Sesterhenn, Isabell , USU, Srivastava, Shiv, USU/Dalgard, Clifton/Wilkerson, Matthew

CPDR

Blood Diseases and Conditions

RFA-1

Wu,Tao-Yiao

Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis in Sleep Disorders

Rothwell, Stephen W, USU

OBG

Sleep Disorders

RFA-1

Zhang, Yumin

Inhibition of endocannabinoid hydrolysis in sleep disorder associated with PTSD

Mueller, Gregory, USU/Tanaka, Mikiei /Moran, Sean

APG

Sleep Disorders

RFA-1

Zhou,Xiaoming

Proteomic identification of urinary biomarkers for sickle nephropathy

Ackerman, Dr. Hans, NHLBI/Oliver, Col James D (WRNMMC)/Knepper, Mark A (NHLBI)

Medicine

Blood Diseases and Conditions

RFA-1