Our Informatics Core offers a variety of resources and data support services to CNRM’s core facilities, funded research projects, and collaborative research projects. These resources and services accommodate all stages of a project’s life cycle (e.g., from protocol development through study closeout and analysis) and a broad range of data and data types (e.g., from preclinical studies to clinical trials).

The Informatics Core currently serves over 34 CNRM research protocols conducted at 8 locations: the Walter Reed National Military Medical Center, the National Institutes of Health, the Uniformed Services University, Suburban Hospital, Washington Hospital Center, Fort Belvoir Community Hospital, the Portland VA, and Oregon Health and Science University. To date, the CNRM Informatics Core manages over 1.9 million records within its data warehouse and data repository.

The Informatics Core manages various platforms for data collection, capture, cleaning, storage, and secure sharing. These platforms include:

The Core also provides a range of support services, offering assistance with:

  • Data collection, retrieval, transfer, auditing, analysis, storage, and backup
  • Software development and testing
  • Quality assurance
  • Case Report Form (CRF) and Electronic Case Report Form (E-CRF) creation/setup
  • Global Unique Identifier (GUID) generation and management
  • Completion of data sharing agreements, especially with the Defense Health Agency’s Data Sharing Agreement Application
  • Statistical development and analysis to include data modeling and machine learning
  • Data management related to CNRM’s Data Repository and to the Federal Interagency Traumatic Brain Injury Research (FITBIR)
  • Informatics consultation (e.g., identification of a project’s resources and needs)

Our Informatics Core ensures each study participates in the traumatic brain injury (TBI) research community’s data standardization efforts. It requires projects to incorporate the National Institute of Neurological Disorders and Stroke’s TBI common data elements, unique data elements, and form structure. It also facilitates the submission of de-identified data to CNRM’s Data Repository and to the FITBIR informatics system. 

New Initiatives

In January 2019, the Informatics Core launched its newest initiative, the Collection, Access, Sharing, and Analytics Platform (CASA). CASA is a secure, web-based application that supports flexible data capture and reporting. It contains three main system components:

  1. An electronic data capture and storage system
  2. CNRM's Data Repository
  3. Data analytic abilities (e.g.,visualization, computation, analysis, and statistical consulting)

CASA is able to accommodate data from human subjects, animal, and biospecimen research projects. With CASA, study investigators have full access to and control over their data sets in real time. Additionally, each investigator is able to determine who has access to their data, each person’s degree of data access, and the duration of data access.

Most recently, the Informatics Core has been working with the newly formed Translational Therapeutics Core and the Optimizing Ferret TBI Experiment to develop experimental designs and data management. The Informatics Core also works with the Clinical Trials Unit (CTU) to provide study design and data support for their current and upcoming clinical trials.

Please send all inquiries and questions for the Informatics Core to