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Center for Neuroscience and Regenerative Medicine

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Defense Health Program
Department of Defense Psychological Health and Traumatic Brain Injury Research Program and JPC-8
Funding Opportunities for Fiscal Year 2018 (FY18)

The FY18 Defense Appropriation provides $125 million (M) to the Department of Defense Psychological Health/Traumatic Brain Injury Research Program (PH/TBIRP) to support critical traumatic brain injury (TBI)- and psychological health (PH)-related research and development efforts to benefit Service members, Veterans, and other beneficiaries of the military health system. As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency (DHA) J9, Research and Development Directorate, manages the Defense Health Program’s Research, Development, Test, and Evaluation appropriation. The U.S. Army Medical Research and Materiel Command (USAMRMC) Congressionally Directed Medical Research Programs (CDMRP) provides execution management support for DHA research program areas, including the Joint Program Committee-8/Clinical and Rehabilitative Medicine Research Program (JPC-8/CRMRP). The managing agent for this Program Announcement is the CDMRP with strategic oversight from the JPC-8/CRMRP.

The PH/TBIRP is providing the information in this pre-announcement to allow investigators time to plan and develop applications. FY18 PH/TBIRP Complex TBI Rehabilitation Research (CTRR) Program Announcements and General Application Instructions for the following award mechanisms are anticipated to be posted on the Grants.gov website in June 2018. Pre-application and application deadlines will be available when the Program Announcements are released. This pre-announcement should not be construed as an obligation by the government.

The full press release can be found here.

 

Defense Health Program
Department of Defense Psychological Health and Traumatic Brain Injury Research Program and JPC-6
Funding Opportunities for Fiscal Year 2018 (FY18)

The FY18 Defense Appropriation provides $125 million (M) to the Department of Defense Psychological Health/Traumatic Brain Injury Research Program (PH/TBIRP) to support critical PH- and TBI-related research and development efforts to benefit Service members, Veterans, and other beneficiaries of the military health system. As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency, J9 Research and Development Directorate manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation. The managing agent for the anticipated Program Announcement/Funding Opportunity is the Congressionally Directed Medical Research Programs (CDMRP) at the U.S. Army Medical Research and Materiel Command (USAMRMC). The CDMRP provides PH/TBIRP execution management support for DHP core research program areas, including the Joint Program Committee 6/ Combat Casualty Care Research Program (JPC-6/CCCRP). JPC-6/CCCRP provides strategic oversight for the PH/TBI funds associated with this funding Program Announcement. The Defense Health Agency is working in collaboration with the U.S. Department of Veterans Affairs (VA) and other Federal agencies on research efforts to improve the lives of Service members and Veterans affected by traumatic brain injury, posttraumatic stress disorder, and other mental health conditions.

The PH/TBIRP is providing the information in this pre-announcement to allow investigators time to plan and develop applications. The FY18 PH/TBIRP Program Announcement and General Application Instructions for the following award mechanism is anticipated to be posted on the Grants.gov website in July 2018. Pre-application and application deadlines will be available when the Program Announcement is released. This pre-announcement should not be construed as an obligation by the Government.

The link to the full release can be found here.

-    Army 'Leans In' To Protect A Shooter's Brain From Blast Injury:  NPR interviews Ms. Tracie Lattimore and Dr. David Brody about effects of blast from shooting weapons.

-    Dr. David Brody and military TBI profiled on "Full Measure." The news organization "Full Measure," released two videos this past week that profile military TBI.  Both videos feature Dr. David Brody, Director of CNRM, and Mr. Frank Larkin, whose son Ryan donated his brain to the CNRM Brain Tissue Repository.  Links to each video are below:

Traumatic Brain Injury 

Ryan's Story

-    Dr. Dan Perl's research on blast-related TBI and PTSD in the military highlighted on "60 Minutes," watch video here.

 

About CNRM

The Center for Neuroscience and Regenerative Medicine is a NIH-USUHS military traumatic brain injury research group with the mission of conducting great science to improve outcomes for our Service Members who suffer from TBI. Founded in 2008 as a Congressionally mandated program, CNRM has grown in the last ten years to include:

  • A total of 71 preclinical and 56 clinical research projects funded by CNRM with 34 currently ongoing
  • Ongoing research at 9 locations in the National Capital Area
  • Enrollment of over 5,170 research participants
  • Over 250 publications from CNRM supported projects
  • Over 80 HJF employees located at the Uniformed Services University (USU), multiple Institute's at the National Institutes of Health (NIH), USU Twinbrook, Walter Reed National Military Medical Center (WRNMMC), Fort Belvoir Community Hospital (FBCH), Washington Hospital Center, and Suburban Hospital

Vision

The past decade of work has positioned CNRM for its next decade, one that carries a new focus on interventional trials in TBI and its co-morbidities in both preclinical and clinical settings. Under the direction of Dr. David Brody and Dr. Leighton Chan, CNRM’s vision for the future is the following:

  • In 2 years, CNRM will be actively running multiple studies testing treatments in human patients, and tests of new therapies in animal models that closely mimic studies in human patients.
  • In 5 years, CNRM will be fully implementing a scientifically rigorous, well organized, and highly focused military traumatic brain injury research program that has twice the funding of our current program. Our early results will have already started to improve outcomes.
  • In 10 years, CNRM will have developed a substantial body of knowledge about what works and what doesn’t for military traumatic brain injury patients. This knowledge will be used around the world to improve outcomes.

Values 

CNRM is committed to excellence in research to advance medical solutions that will improve outcomes for our Service Members who suffer from TBI and its co-morbidities. The Center embraces a set of values by which investigators and staff work toward effective treatments for TBI:

  • A sense of urgency towards improving outcomes for military traumatic brain injury patients
  • Solutions-focused
  • Collaborative with other research groups in the national capital area and around the world
  • Fiscally responsible, generating real world value for tax-payer money
  • Transparency: we will publish and disseminate all of our findings, regardless of whether the treatments work or not

Solving the problem of TBI is not a solo effort; it will take the active participation of our investigators and staff as well as our partners within DoD, the U.S., and abroad, and, most importantly, the men and women who volunteer to participate in our studies to find effective therapies.  Together, we can all make a difference in TBI research.

                                    

  Together We Can Make A Difference