CNRM hosts a monthly seminar series that features presentations from experts in the traumatic brain injury (TBI) research community. These seminars are critical because they give current and future experts within the TBI community an opportunity to gather together and exchange ideas. By working together, we can all make a difference in TBI research. See below for more information about previous and upcoming CNRM seminars.
Title: "Advances in the CHIMERA Animal Model of Traumatic Brain Injury"
: Dr. Wellington's presentation will describe new studies using the Closed Head Impact Model of Engineered Rotational Acceleration
(CHIMERA), an animal model of TBI that places equal emphasis on the biomechanical and neurological relevance to human TBI. She will also describe new design features for the CHIMERA platform and give an overview of her TBI translational activities spanning CHIMERA and human neurotrauma.
University of Washington, School of Medicine
Title: "Combat-related Concussion: Understanding Trajectories of Long-term Clinical and Imaging Outcomes"
Presentation Summary: This presentation will feature findings from a prospective, observational, and longitudinal research study that followed Service Members from the point of injury in combat out to 1-year, 5-year, and, now, 10-year outcomes. Known as the EVOLVE study (EValuation Of mild TBI Long-term outcome in Active-Duty US Military and VEterans) the effort focused on elucidating the effects of mild brain injury sustained in combat to outcomes and connecting the dots through repeated evaluations over the first decade post-injury. Results from both the advanced neuroimaging and extensive battery of neurological, neuropsychological, and psychiatric outcomes collected in these patients will be presented.
Title: "Mean Apparent Propagator (MAP) MRI: Potential Applications to Imaging TBI?"
Presentation Summary: Dr. Basser and Dr. Butman will review their recent work, performed within CNRM, in developing and implementing a novel diffusion MRI pipeline to try to detect TBI in a clinical setting.
Co-Founder & Chief Science Officer
Title: "Cerebrovascular Assessments after Traumatic Brain Injury"
Presentation Summary: Dr. Hamilton’s presentation discussed the various capabilities of Neural Analytics’ Transcranial Doppler Ultrasound System. This portable system noninvasively assesses post-concussive cerebrovascular reactivity by measuring blood flow changes in the brain.
Professor of Pharmacology & Neuroscience, Uniformed Services University
Chair, CNRM’s Biospecimen Repository Steering Committee
Johns Hopkins University School of Medicine
Title: "Mass-Spectrometric Analysis of Lipids in Brain & Blood after TBI: Lipids as Potential Biomarkers for TBI"
- Subjects with mild TBI and “injury positive” magnetic resonance imaging (MRI) scans
- Subjects with mild TBI and “injury negative” MRI scans
- Age/gender-matched controls with no history of TBI
- Impact-related TBI within civilian subjects
- Blast-related TBI within military subjects
This project’s objective was to determine if changes in specific lipids or lipid profiles correlated with injury type (e.g., cause), severity, location, and clinical outcomes.