Over 200 million Neisseria gonorrhoeae (Ng) and sexually transmitted Chlamydia trachomatis (Ct) infections occur world-wide each year. Concurrent infections are also common, yet little is known about the clinical aspects or pathogenesis of gonococcal/chlamydial coinfection. The goals of the Atlantic Coast Sexually Transmitted Infections Cooperative Research Center (AC STI CRC) are to further the understanding of the immunobiology of gonorrhea, chlamydial infection, and gonorrhea/chlamydial coinfections with the aim of developing novel immunotherapies and a gonorrhea vaccine. We also investigate the genetic basis behind the spread of antibiotic resistance in Ng which is of global concern and threatens current control measures. Integrated throughout many projects within the Center is the development of innovative models for investigating different aspects of Ng/Ct coinfection, which heretofore have not been studied due in part to a lack of experimental systems.
AC STI CRC
Uniformed Services University of the Health Sciences
Department of Microbiology and Immunology
4301 Jones Bridge Road
Bethesda, Maryland 20814-4799
Phone: (301) 295-3400
FAX: (301) 295-1545