Edward Mitre, M.D.

Edward Mitre, M.D.

Name: Edward Mitre, M.D.

USU Department of Primary Appointment: 
Microbiology and Immunology
Faculty Rank: 
Associate Professor
Location: 
Uniformed Services University of the Health Sciences, Bethesda, MD

Research Interests:
Immunology, Host Defenses
Basic Biology of Bacterial, Viral, or Parasite Diseases

Office Phone: 
(301) 295-1958

Education

2001 Infectious Diseases Fellowship, NIAID, NIH, Bethesda, MD
1998 Internal Medicine Residency, New York University, New York, NY
1995 M.D., Johns Hopkins University School of Medicine, Baltimore,
1991 B.A., Biology, Columbia University, New York, NY

Biography

Edward Mitre is an Associate Professor in the Department of Microbiology and Immunology at the Uniformed Services University in Bethesda, Maryland. He obtained his medical degree from the Johns Hopkins School of Medicine in 1995 and then completed an internal medicine residency at New York University. He then did an infectious diseases fellowship at the National Institutes of Health, followed by post-doctoral research work in helminth immunology as well as clinical training in tropical medicine at the Laboratory of Parasitic Diseases at the NIH. Dr. Mitre’s laboratory studies the biology, immunology, and pathogenesis of filarial infections and allergic diseases. Filariae are tissue-invasive nematodes that cause diseases such as elephantiasis and river blindness. Current studies in Dr. Mitre’s laboratory are focused on identifying novel drug and vaccine targets in filarial nematodes, evaluating natural products for the treatment of filariae, developing helminth-derived therapies for allergy and autoimmunity, and elucidating the mechanisms that drive immunoregulation in chronic helminth infections and allergy immunotherapy. In addition to his laboratory research and teaching responsibilities at the Uniformed Services University, Dr. Mitre regularly attends on the internal medicine and infectious diseases services at the Walter Reed National Military Medical Center.

Representative publications, projects, and/or deployments

  • Morris, C.P., Bennuru, S., Kropp, L.E., Zweben, J.A., Meng, Z., Taylor, R.T., Chan, K., Veenstra, T.D., Nutman, T.B., and Mitre, E., “A proteomic analysis of the body wall, digestive tract, and reproductive tract of Brugia malayi.” PLoS Neglected Tropical Diseases, 2015, 9(9):e0004054.
  • Evans, H., Killoran, K.E., Mitre, B.K., Smith, M.A., Morris, C.P., Kim, S. and Mitre, E. “Ten weeks of infection with a tissue-invasive helminth protects against immune complex-mediated inflammation but not clinical type I hypersensitivity in previously sensitized mice.” Journal of Immunology, 2015, 195(7):2973-84.
  • Fox, E.M., Torrero, M., Evans, H., and Mitre, E. “Immunologic characterization of three murine regimens of allergen-specific immunotherapy.” Journal of Allergy and Clinical Immunology, 2015, 135(5):1341-51.
  • Evans, H. and Mitre, E., “Worms as therapeutics for allergy: understanding why benefits in animal studies have not translated into clinical success.” Journal of Allergy and Clinical Immunology, 2015, 135(2):343-53.

Bibliography

  • Commendation Letter from Major General Jeffrey B. Clark, U.S. Army, on behalf of Walter Reed National Military Medical Center, “For meritorious service while serving as a health care provider to a critically ill and complex patient in the Medical ICU" 2016
  • Outstanding Lecturer of the Preclinical Years (USU SOM classes of 2009, 2012, 2016-18)
  • Outstanding Civilian Educator Award, USU SOM class of 2016
  • Chair, American Society of Tropical Medicine and Hygiene Young Investigator Competition 2016-present (member and judge, 2008-15)
  • Associate Editor PLoS Pathogens 2014-present
  • Chair, Filariasis Section, American Society of Tropical Medicine and Hygiene Annual Meeting Committee, 2010-2013 (member 2007-2009)
  • Senior Chief Resident in Internal Medicine, New York University, 1998-1999