Saibal Dey, PhD
Saibal Dey, PhD

Name: Saibal Dey, PhD
Research Interests:
Membrane Transport
Multidrug Resistance
Education
M. Sc., Zoology, Specialization: Cell Biology, University of Burdwan, West Bengal, India (1985)
B. Sc., Zoology, Minor: Botany and Chemistry, University of Burdwan, West Bengal, India (1983)
Representative publications, projects, and/or deployments
- Vice Chair, Department of Biochemistry
- Dean's Fellow, Uniformed Services University School of Medicine, (2018)
- Module Director, Foundation in Medicine Module, Molecules to Military Medicine Curriculum, USU School of Medicine
- "School of Medicine Dean's Teaching Award" in Basic Science, Uniformed Services University School of Medicine (2017)
- “Hébert Impact Award” for outstanding contribution to the mission of the School, Uniformed Services University School of Medicine (2016)
- “Hébert Impact Award” for outstanding contribution to the mission of the School, Uniformed Services University School of Medicine (2015)
- “Recognition For Exemplary Support of the Molecules to Military Medicine Curriculum” Uniformed Services University School of Medicine Curriculum Reform (2011)
- “Plank Holders of the Molecules to Military Medicine Curriculum”, for contribution to curriculum reform, Dean’s Office, Uniformed Services University School of Medicine (2011)
- “Fellows Award for Research Excellence”, National Institutes of Health, Bethesda, Maryland. (1999)
- “AACR-Genetics Institute Young Investigator Award”, in the annual meeting of The American Association For Cancer Research (1998)
Bibliography
- Mandal, D., Moitra, K., Ghosh, D., Xia, D. and Dey, S. (2012) Evidence for modulatory sites at the lipid-protein interface of the human multidrug transporter P-glycoprotein. Biochemistry 51:2852-2866
- Data, S., Mazumder, S., Ghosh, D., S., Dey, S., and Bhattacharya, S. (2009) Low concentration of arsenic induce caspase-3 mediated head kidney macrophage apoptosis with JNK-p38 activation in Claris batrachas. Toxicology and Applied Pharmacology 241:329-338
- Fong, W. F., Wan, C. K., Zhu, G. Y., Chattopadhyay, A., Dey S., Zhao, Z., and Shen, X. L. (2007) Schisandrol A from Schisandra chnensis reverses P-glycoprotein-mediated multidrug resistance by affecting Pgp-substrate complexes. Planta Medica, 73: 212-220.
- Wan, C. K., Zhu, G. Y., Shen, X. L., Chattopadhyay, A., Dey, S., and Fong, W. F. (2006) Gomisin A alters substrate interaction and reverses P-glycoprotein mediated multidrug resistance in HepG2-DR cells. Biochemical Pharmacology, 72(7): 824-37
- Maki, N., and Dey, S. (2006) Biochemical and pharmacological properties of an allosteric modulator site of human P-glycoprotein. Biochemical Pharmacology 72(2): 145-155
- Maki, N., Moitra, K., Ghosh, P., and Dey, S. (2006) Allosteric modulation bypasses requirement for ATP hydrolysis in regenerating low-affinity transition state conformation of human P-glycoprotein. Journal of Biological Chemistry. 281(16): 10699-10777
- Ghosh, P., Moitra, K., Maki, N., and Dey, S. (2006) Allosteric modulation of the human P-glycoprotein involves conformational changes mimicking catalytic transition intermediates. Archives of Biochemistry and Biophysics. 450 (1): 100-112
- Maki, N., Moitra, K., Silver, C., Ghosh, P., Chattopadhyay, A. K., and Dey, S. (2006) Modulator induced interference in functional cross talk between the substrate- and the ATP- sites of human P-glycoprotein. Biochemistry 45: 2739-2751
- Maki, N., Hafkemeyer, P., and Dey, S. (2003). Allosteric modulation of human P-glycoprotein: Inhibition of transport by preventing substrate translocation and dissociation. Journal of Biological Chemistry. 278(20): 18132-18139.
- Dey, S. (2002) Biricodar (Vertex Pharmaceuticals). Current Opinion in Investigational Drugs, Vol. 3(5): 818-823.