Stephen Davies, B.V.Sc., Ph.D.
Stephen J. Davies, B.V.Sc., Ph.D.
Name: Stephen J. Davies, B.V.Sc., Ph.D.
Basic Biology of Bacterial, Viral, or Parasite Diseases
Immunology, Host Defenses
Ph.D. ~ College of Veterinary Medicine, Cornell University, United States, 1998
Postdoctoral Fellow ~ Department of Pathology, University of California San Francisco, United States, 1998-2004
• Elucidation of host factors that modulate schistosome blood fluke development
• Initiation of innate immune responses by schistosomes and other helminths
• Immune evasion by schistosomes and other helminths
• Role of helminth proteases in immune responses to helminths
• Elucidation of helminth signaling pathways that transduce host signals
• Exploitation of helminth protein kinases as novel drug targets
• Mucosal immune responses to Enteroaggregative Escherichia coli
- Riner, D.K., Ferragine, C.E., Maynard, S.K., Davies, S.J. (2013) Regulation of innate responses during pre-patent schistosome infection provides an immune environment permissive for parasite development. PLoS Pathogens 2013;9(10):e1003708. doi: 10.1371/journal.ppat.1003708
- Lamb, E.W., Walls, C.D., Pesce, J.T., Riner, D.K., Maynard, S.K., Crow, E.T., Wynn, T.A., Schaefer, B.C., and Davies, S.J. (2010) Blood fluke exploitation of non-cognate CD4+ T cell help to facilitate parasite development. PLoS Pathogens 6(4):e1000892
- Swierczewski, B.E. and Davies, S.J. (2009) A Schistosome cAMP-Dependent Protein Kinase Catalytic Subunit is Essential for Parasite Viability. PLoS Negl. Trop. Dis. 3(8), e505
- Davies, S.J., Grogan, J.L., Blank R.B., Lim, K.C., Locksley, R.M. and McKerrow, J.H. (2001) Modulation of Blood Fluke Development in the Liver by Hepatic CD4+ Lymphocytes. Science 294, 1358-1361