Volodymyr Pidoplichko, Ph.D.

Volodymyr Pidoplichko, Ph.D.

Name: Volodymyr Pidoplichko, Ph.D.

USU Department of Primary Appointment: 
Anatomy, Physiology and Genetics
Title: 
Research Associate Professor
Faculty Rank: 
Associate Professor
Location: 
Walter Reed National Military Medical Center, Bethesda, MD

Research Interests:
The role of CNS ligand-gated ion channels in Amygdala
Modulation of Amygdala network by Acid Sensitive Ion Channels (ASIC1aRs)

Education

Faculty of Physics of Shevchenko State University in Kyiv, Ukraine. Ph.D. in biophysics and electrophysiology from Bogomoletz Institute of Physiology, Kyiv, Ukraine.

Biography

NAME: Volodymyr Pidoplichko

ACADEMIC TRAINING:
1965 - 1970 Kiev State University (Faculty of Physics, B.S. in Molecular Physics)

1969 -1972,
1974 -1975 Ph.D. ( “Candidate of Biol. Sciences” ) Bogomoletz Institute of Physiology, Ukr.
Acad. Sci., Kyiv, Ukraine
1975 - 1987 “Doctor of Biol. Sciences“ , senior sci. degree

EMPLOYMENT:
1970 - 1972 Research Fellow with Dr. P.G.Kostyuk,
Bogomoletz Institute of Physiology, Kiev, Ukraine
1972 - 1974 Lieutenant-Engineer, ground control radar, Soviet Air Force
1974 - 1980 Junior Research Scientist,
Dr. P.G.Kostyuk, Chairman,
Bogomoletz Institute of Physiology, Kiev, Ukraine
1980 - 1988 Senior Research Scientist, Bogomoletz Institute of Physiology, Kiev, Ukraine
1988 - 1989 Senior Research Scientist,
Dr. Yu. Yu. Gleba, Dept. Head,
Div. of Cell Biology and Engineering, Institute of Botany, Kiev, Uktaine
1989 - 1990 Head of the Laboratory of Molecular Physiology,
Dr. Yu. Yu. Gleba, Chairman,
Institute of Cell Biology and Engineering, Kiev, Ukraine
1991 - 1992 Head of the Department of Membranology and Phytochemistry,
Dr. K.M.Sytnik, Chairman,
Institute of Botany, Kiev, Ukraine
1992 - 1995 Research Scientist,
Dr. K. G. Reymann, Dept. Head,
Institute for Neurobiology, Magdeburg, Germany
1995 - 1996 Head of the Dep. of Membranology and Phytochemistry,
Dr. K.M.Sytnik, Chairman,
Institute of Botany, Kiev, Ukraine
1996 - 2006 Research Associate/Instructor,
Dr. John A. Dani,
Div. of Neuroscience, Baylor College of Medicine, Houston, USA
2007-20xx Research Associate
Prof. Dr. Maria F. Braga,
Dep. of Anatomy, Physiology and Genetics, Uniformed Services
University of the Health Sciences, Bethesda, USA
20xx-present Research Associate Professor
Prof. Dr. Maria F. Braga,
Dep. of Anatomy, Physiology and Genetics, Uniformed Services
University of the Health Sciences, Bethesda, USA

Representative publications, projects, and/or deployments

  • 1983 Recipient State prize USSR Council of Ministers
  • Pidoplichko V.I. & Verkhratsky A.N. (1984) Possible existence of tetrodotoxin-sensitive voltage-dependent chloride conductance in the membrane of perfused cardiomyocytes. Doklady Akad. Nauk SSSR, Moscow, v.279, pp.1012-1015 (in Russian)
  • Wilsch V.W., Pidoplichko V.I., Opitz T., Shinozaki H. & Reymann K.G. (1994) Metabotropic glutamate receptor agonist DCG-IV as NMDA receptor agonist in immature rat hippocampal neurons. Eur. J. Pharmacol. v.262, pp.287-291
  • Pidoplichko V.I., Wilsch V.W. & Reymann K.G. (1996) Fast desensitizing kainate-gated current resolved in whole-cell experiments on isolated rat hippocampal neurons. Eur. J. Pharmacol., v. 303, pp.145-149
  • Pidoplichko V.I. (1996) Dependence of solution exchange time on cell or patch linear dimensions in concentration jump experiments using patch-clamped sensory neurons. Pflugers Arch. - Eur. J. Physiol. v. 432, pp. 1074-1079
  • Pidoplichko VI, Dani JA. (2005) Applying small quantities of multiple compounds to defined locations of in vitro brain slices. J Neurosci Methods. v.142(1), pp.55-66.
  • Pidoplichko VI, Dani JA. (2006) Acid-sensitive ionic channels in midbrain dopamine neurons are sensitive to ammonium, which may contribute to hyperammonemia damage. Proc Natl Acad Sci U S A. v.103(30) pp.11376-80.

Bibliography

  • Kostyuk P.G., Krishtal O.A. & Pidoplichko V.I. (1972) Potential-dependent membrane current during the active transport of ions in snail neurones. J.Physiol., London, v.226, pp.373-392
  • Krishtal O.A. & Pidoplichko V.I. (1975) Intracellular perfusion of snail giant neurons. Neirofiziologiya, Kiev, v.7, pp.327-329 (in Russian)
  • Kostyuk P.G., Krishtal O.A. & Pidoplichko V.I. (1975) Effect of internal fluoride and phosphate on membrane currents during intracellular dialysis of nerve cells. Nature, London, v.257, pp.691-693
  • Kostyuk P.G., Krishtal O.A. & Pidoplichko V.I. (1977) Asymmetrical displacement currents in nerve cell membrane and effect of internal fluoride. Nature, London, v.267, pp.70-72
  • Krishtal O.A. & Pidoplichko V.I. (1980) A receptor for protons in the nerve cell membrane. Neuroscience, v.5, pp.2325-2327
  • Kostyuk P.G., Krishtal O.A. & Pidoplichko V.I. (1981) Calcium inward current and related charge movements in the membrane of snail neurones. J.Physiol., London, v.310, pp.403-421
  • Krishtal O.A., Marchenko S.M. & Pidoplichko V.I. (1983) Receptor for ATP in the membrane of mammalian sensory neurones. Neuroscience Letters, v.35, pp.41-45
  • Pidoplichko V.I. (1992) Ammonia and proton-gated channel populations in trigeminal ganglion neurons. Gen Physiol. Biophys., v.11, pp.39-48
  • Pidoplichko V.I. , DeBiasi M., Williams J.T. & Dani J.A.(1997) Nicotine activates and desensitizes midbrain dopamine neurons. Nature, v.290, pp. 401-404
  • Pidoplichko V.I., Aroniadou-Anderjaska V, Prager E.M., Figueiredo T.H., Almeida-Suhett C.P., Miller S.L. & Braga M.F. (2014) ASIC1a activation enhances inhibition in the Basolateral Amygdala and reduces anxiety. J.Neuroscience, v.34(9), pp.3130-3141