William Catherino, M.D., Ph.D.

William H. Catherino, M.D., Ph.D.

Name: William H. Catherino, M.D., Ph.D.

USU Department of Primary Appointment: 
Obstetrics and Gynecology
Title: 
Professor and Research Head
Faculty Rank: 
Full Professor
Location: 
Uniformed Services University of the Health Sciences, Bethesda, MD

Research Interests:
Reproductive Endocrinology and Infertility / Obstetrics and Gynecology
Uterine Fibroids

Office Phone: 
(301) 295-3126

Education

B.S. (Honors): University of Michigan
M.D. (AOA): University of Wisconsin-Madison
Ph.D.: University of Wisconsin-Madison
Residency (OBG): Duke University
Fellowship (REI): National Institutes of Health

Biography

Dr. Catherino graduated from the University of Michigan (High Honors and High Distinction) with a Bachelors of Science and the University of Wisconsin-Madison (Alpha Omega Alpha) with M.D. and Ph.D. degrees. He completed his Obstetrics and Gynecology Residency at Duke University Medical Center and his Reproductive Endocrinology and Infertility fellowship at the Combined Federal Fellowship (NIH, WRAMC, NNMC, USUHS). After completing his fellowship, he joined the faculty at the Uniformed Services University of the Health Sciences, while providing patient care at WRNMMC and the NIH. Additionally, he completed additional scholarly training as part of the American Association of Obstetricians and Gynecologists Foundation.

During his 13 years in the Department of Obstetrics and Gynecology at the Uniformed Services University, Dr. Catherino served in a variety of clinical, research, and academic roles including Associate Program Director of the Reproductive Endocrinology and Infertility fellowship, mentor to over 50 scientists at all levels of their training (from high school to post-graduate level), and as a National Faculty Educator for USUHS . He has also played a central role in the Departmental efforts to combine the OBG research resources of WRNMMC and USUHS as part of the Unity of Effort initiative.

Academically, he holds the rank of Professor of Obstetrics and Gynecology at USU and he has authored or co-authored over 100 peer-reviewed manuscripts. He has numerous teaching accolades, and is sought out to provide unique exposure to the science, medicine, and ethics of his field. While at USUHS, he has record of outstanding service to both the undergraduate, graduate, and post-graduate medical education programs.

Representative publications, projects, and/or deployments

  • Islam MS, Catherino WH, Protic O, Janjusevic M, Gray PC, Giannubilo SR, Ciavattini A, Lamanna P, Tranquilli AL, Petraglia F, Castellucci M, Ciarmela P. Role of activin-A and myostatin and their signaling pathway in human myometrial and leiomyoma cell function. J Clin Endocrinol Metab 2014;99:E775-85.
  • Tinelli A, Mettler L, Malvasi A, Hurst B, Catherino W, Myanbaev OA, Guido M, Alkatout I Schollmeyer T. Impact of surgical approach on blood loss during intracapsular myomectomy. Minim Invasive Ther allied Technol 2014;23:87-95.
  • National Faculty Educator (USUHS)
  • Ira and Ester Rosenwaks Young Investigator Award (ASRM)
  • Seminal Article-Fertility and Sterility
  • Prize Paper Winner (ASRM)
  • Chair, Postgraduate Course on Uterine Leiomyomas (multiple, ASRM, SRI)
  • Chair, Fibroid Special Interest Group (ASRM)
  • Oral Boards Examiner and Question Writer for Oral and Written Exam (REI)
  • Inductee-American Gynecologic and Obstetric Society

Bibliography

  • Stewart EA, Laughlin-Tommaso SK, Catherino WH, Lalitkumar S, Gupta D, Vollenhoven B. Uterine fibroids. Nat REve Dis Primers 2016;2:16043.
  • Patel A, Malik M, Britten J, Cox J, Catherino WH. Mifepristone extracellular matrix formation in uterine leiomyomas. Fertil Steril 2016;105:1102-10.
  • Protic O, Toti P, Islam MS, Occhini R, Giannubilo SR, Catherino WH, cinti S, Petraglia F, Ciavattini A, Castellucci M, Hinz B, Ciarmela P. Possible involvement of inflammatory/reparative processes in the development of uterine fibroids. Cell Tissue REs 2016;364:415-27.
  • Green KA, Zarek SM, Catherino WH. Gynecologic health and disease in relation to the microbiome of the female reproductive tract. Fertil Steril 2015;104:1351-7.
  • Malik M, Britten J, Cox J, Patel A, Catherino WH. Gonadotropin-releasing hormone analogues inhibit leiomyoma extracellular matrix despite presence of gonadal hormones. Fertil Steril 2016;105:214-24.
  • Drayer SM, Catherino WH. Prevalence, morbidity, and current medical management of uterine leiomyomas. Int J Gynaecol Obstet 2015;131:117-22.
  • Patel A, Malik M, Britten J, Cox J, Catherino WH. Alternative therapies in management of leiomyomas. Fertil Steril 2014;102:649-55.
  • Malik M, Britten J, Segars J, Catherino WH. Leiomyoma cells in 3-dimensional cultures demonstrate an attenuated response to fasudil, a rho-kinase inhibitor, when compared to 2-dimensional cultures. Reprod Sci 2014;21:1126-38.
  • Islam MS, Protic O, Ciavattini A, Giannubilo SR, Tranquilli AL, Catherino WH, Castellucci M, Ciarmela P. Tranilase, an orally active antiallergic compound, inhibits extracellular matrix production in human uterine leiomyoma and myometrial cells. Fertil Steril 2014;102:597-606
  • Levy G, Malik M, Britten J, Gilden M, Segars J, Catherino WH. Liarozole inhibits transforming growth factor beta 3 mediated extracellular matrix formation in human three-dimensional leiomyoma cultures. Fertil Steril 2014;102:272-81.