Education1983 A.S. BMET, Pennsylvania State University, Wilkes-Barre, PA
1989 B.S. Electrical Engineering, Lehigh University, Bethlehem, PA
1993 M.E. Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA
1994 Ph.D. Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA
Dissertation: "Monitoring Therapeutic Intervention in Cancer and Stroke using Quantitative Magnetic Resonance Imaging", (Mentor: Christopher H. Sotak, Ph.D.)
1994 – 1996 Postdoctoral Scholar, Center for NMR Research, The Milton S. Hershey Medical Center of The Pennsylvania State University College of Medicine, "1H and 31P NMR in Neonatal Hypoxia Ischemia" (Mentor: Michael B. Smith, Ph.D.)
1983 Deborah Heart and Lung Center Browns Mills, NJ
BiographyDr. Dardzinski is an Associate Professor in the Department of Radiology and Radiological Sciences at USUHS and the PI of the CNRM's Translational Imaging Facility at USUHS. His areas of expertise include development of magnetic resonance imaging (MRI) techniques and optimization of other imaging modalities to improve understanding of disease processes such as traumatic brain injury, stroke, and musculoskeletal disorders. He joined USUHS from the Children’s Hospital of Philadelphia, where he focused on musculoskeletal research and whole-body imaging in children. Dr. Dardzinski received his Ph.D. in Biomedical Engineering from Worcester Polytechnic Institute in 1994 where he employed nuclear magnetic resonance (NMR) to evaluate stroke and tissue oxygenation in animal models via diffusion and fluorine imaging, respectively, under the mentorship of the late Dr. Chris Sotak. He conducted his fellowship at the Pennsylvania State University at Hershey, where he collaborated with Dr. Timothy Mosher to develop “T2 mapping”, a measure of early cartilage disruption that is now widely used in musculoskeletal research and practice. He then joined the faculty at the Cincinnati Children’s Hospital Medical Center for over a decade, where for the last two years he was named Scientific Director of the Imaging Research Center in Radiology, overseeing all imaging research activities within the hospital, with an academic appointment of Professor of Pediatrics, Radiology, and Biomedical Engineering at the University of Cincinnati. Dr. Dardzinski joined Merck in 2007 as Senior Director/Research Fellow, leading a wide variety of imaging efforts across a broad range of therapeutic areas with the goal of developing novel biomarkers for prediction of outcomes in clinical trials, and for discovery of new drug targets.
Dr. Dardzinski has authored over 75 peer-reviewed publications, presented numerous invited talks, and has served on the Scientific Program and Governance Committees of the International Society for Magnetic Resonance in Medicine (ISMRM). He has further served on several NIH grant committees, abstract review committees, doctoral committees, and internal grant and investigational review boards.
Dr. Dardzinski’s research interests focus on the utility of quantitative imaging for biomarker development in disease diagnosis and for the monitoring of therapeutic efficacy in pre-clinical to clinical translational research and drug development.
Representative publications, projects, and/or deployments
2014 - 2016 Research Associate Professor, Henry Jackson Foundation
2012 - 2014 Sr. Clinical Research Scientist, Department of Radiology, Children’s Hospital of Philadelphia
2007 - 2012 Sr. Director, Merck Research Laboratories, West Point, PA.
2009 - Present Adjunct Professor of Radiology, University of Pennsylvania
2007 Research Professor, Radiology and Pediatrics, University of Cincinnati College of Medicine
2004 - 2007 Division Chief, Radiology Research and the Imaging Research Center, Department of Radiology and Pediatrics, Cincinnati Children’s Hospital Medical Center
2000 - 2007 Director of In Vivo Microimaging Laboratory, Imaging Research Center, Department of Radiology, Cincinnati Children’s Hospital Medical Center
1987 - 1989 Senior Technical Associate, AT&T Bell Laboratories, Allentown, PA
1984 - 1985 Biomedical Engineer, Good Samaritan Hospital, Lebanon, PA