Jeremy Rotty

Ph.D.

Department of Primary Appointment:
School of Medicine
Biochemistry
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Cell Migration
Immunology
Office Phone

Education

Berea College
B.A. in Biology, 2005

The Johns Hopkins School of Medicine
Ph.D. BCMB program, 2011

The University of North Carolina at Chapel Hill
Postdoctoral Fellow, Dept. of Cell Biology and Physiology, 2017

Representative Bibliography

Rotty, JD., Brighton, HE., Asokan, SB., Cheng, N., Ting, JP., and Bear, JE. (2017) Arp2/3 complex is required for macrophage integrin functions but is dispensable for FcR phagocytosis and in vivo motility. Dev Cell. 2017 August 9; 42(5): 498-513.

Rotty, JD and Bear, JE. (2015) Competition and collaboration between different actin assembly pathways allows for homeostatic control of the actin cytoskeleton. BioArchitecture. Review. 2015 Aug 3; 5(1-2):27-34. Epub 2015 Oct. 2.

Rotty, JD., Wu, C., Haynes, EM., Suarez, C., Winkelman, JD., Johnson, HE., Haugh. JM., Kovar, DR., and Bear, JE. (2015) Profilin-1 serves as a gatekeeper for actin assembly by Arp2/3-dependent and –independent pathways. Dev Cell. 2015 Jan 12;32(1):54-67

Rotty, JD., Wu, C., and Bear, JE. (2013) New insights into the regulation and cellular functions of the Arp2/3 complex. Nat. Rev. Mol. Cell Biol. Review. 14(1):7-12

Rotty, JD. and Coulombe, PA. (2012) A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair. J. Cell Biol. 197(3): 381-9