David S. Krantz


Department of Primary Appointment:
School of Medicine
Medical and Clinical Psychology
Professor of Medical and Clinical Psychology; Professor of Psychiatry (secondary)
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Behavioral medicine and cardiovascular disease
Psychosocial stress and human health
Office Phone


Education: B.S. (1971) in Psychology, City College of New York.
Ph.D. (1975) in Psychology, University of Texas at Austin.


Dr. Krantz's broad research interests are on the effects of psychosocial stress on health, and the role of psychological factors in cardiovascular disease. He is involved in several multi-disciplinary research programs relevant to the area of stress and health. For more than 30 years, his primary research focus has been on the effects of acute stress as a trigger of coronary heart disease events, and he has published more than 180 scientific and professional papers in these areas. In his current research, he is Principal Investigator of the BETRHEART Study, which investigates stress and psychosocial factors in the progression of heart failure. In other projects, he collaborates with investigators in the USUHS Psychiatry Department's Center for the Study of Traumatic Stress in areas relating to effects of stress and bereavement on physical health in military populations, and PTSD and sleep disorders in relation to cardiovascular disease. He also is working with colleagues in several medical disciplines to study the relationships of posttraumatic stress disorder, mild traumatic brain injury, and cardiovascular disease among military service members, and continues research in several areas including psychosocial factors and coronary disease in women in the NHLBI WISE study.

Dr. Krantz was formerly Chair of the USUHS Department of Medical and Clinical Psychology between 1999-2014, and was one of a group of founders of the USU Center for Deployment Psychology (CDP), and CDP Principal Investigator between 2006-2015. In the past, he has served as Editor-in-Chief of the APA journal Health Psychology, president of the Health Psychology Division of APA, and president the Academy of Behavioral Medicine Research. He is active in graduate education, and has supervised >24 doctoral dissertations in Medical and Clinical Psychology, trained 11 post-doctoral fellows, and currently has 4 Ph.D. students in his lab. See bios of members of the Cardiovascular Behavioral Medicine Lab here: https://www.usuhs.edu/faculty/krantz, and pictures of our lab group and activities on this page: https://www.usuhs.edu/faculty-staff/david-s-krantz-phd

Representative publications, projects, and/or deployments

Those wishing to use the KRANTZ HEALTH OPINION SURVEY (KHOS) scale can download a copy at this link: https://www.usuhs.edu/sites/default/files/media/mps/pdf/krantzhealthopinionsurveyscale.pdf No additional permission from the author is needed in order to use this scale. Download the original scale development/validation article by Krantz et al. (1980) in Journal of Personality and Social Psychology at this link: https://www.usuhs.edu/sites/default/files/media/mps/pdf/jpsp1980krantzetalkhos.pdf


Krantz DS, Harris KM, Rogers HL, Whittaker KS, Haigney MCP, Kop WJ. Psychological factors and cardiac repolarization instability during anger in implantable cardioverter defibrillator patients. Ann Noninvasive Electrocardiol. 2021 Apr 3:e12848. doi: 10.1111/anec.12848. Online ahead of print. PMID: 33813750

Wawrzyniak, AJ, Bekkouche, NS, Krantz, DS. Acute behavioural and psychological triggers of acute myocardial infarction. In S.R. Waldstein, et al. (Eds.), Handbook of Cardiovascular Behavioral Medicine. NY NY: Springer-Verlag, 2021.

Harris KM, Gottdiener JS, Gottlieb SS, Burg MM, Li S, Krantz DS. Impact of Mental Stress and Anger on Indices of Diastolic Function in Patients With Heart Failure. J Card Fail. 2020 Aug 1;. doi: 10.1016/j.cardfail.2020.07.008. [Epub ahead of print] PubMed PMID: 32750485.

Endrighi R, Dimond AJ, Waters AJ, Dimond CC, Harris KM, Gottlieb SS, Krantz DS. Associations of perceived stress and state anger with symptom burden and functional status in patients with heart failure. Psychology and Health. 2019 Oct;34(10):1250-1266. doi:10.1080/08870446.2019.1609676.

Biggs QM, Ursano RJ, Wang J, Krantz DS, Carr RB, Wynn GH, Adams DP, Dacuyan NM, Fullerton CS. Daily variation in post traumatic stress symptoms in individuals with and without probable post traumatic stress disorder. BMC Psychiatry. 2019 Feb 4;19(1):56. doi: 10.1186/s12888-019-2041-7.

Harris KM, Krantz DS, Kop WJ, Marshall J, Robinson SW, Marshall JM, Gottlieb SS. A New Clinically Applicable Measure of Functional Status in Patients With Heart Failure: The 60-Foot Walk Test. JACC Heart Fail. 2017 Jun;5(6):411-420. doi: 10.1016/j.jchf.2017.02.005. Epub 2017 May 10. PMID: 28501523

Endrighi R, Waters AJ, Gottlieb SS, Harris KM, Wawrzyniak AJ, Bekkouche NS, Li Y, Kop WJ, Krantz DS. Psychological stress and short-term hospitalisations or death in patients with heart failure. Heart. 2016 Jun 29. pii: heartjnl-2015-309154. doi: 10.1136/heartjnl-2015-309154. [Epub ahead of print] PMID: 27357124

Wawrzyniak AJ, Dilsizian V, Krantz DS, Harris KM, Smith MF, Shankovich A, Whittaker KS, Rodriguez GA, Gottdiener J, Li S, Kop W, Gottlieb SS. High Concordance Between Mental Stress-Induced and Adenosine-Induced Myocardial Ischemia Assessed Using SPECT in Heart Failure Patients: Hemodynamic and Biomarker Correlates. J Nucl Med. 2015 Oct;56(10):1527-33. doi: 10.2967/jnumed.115.157990. Epub 2015 Jul 23. PMID: 26205303

Gottlieb SS, Harris K, Todd J, Estis J, Christenson RH, Torres V, Whittaker K, Rebuck H, Wawrzyniak A, Krantz DS. Prognostic significance of active and modified forms of endothelin 1 in patients with heart failure with reduced ejection fraction. Clin Biochem. 2015 Mar;48(4-5):292-6. doi: 10.1016/j.clinbiochem.2014.12.012. Epub 2014 Dec 23. PMID: 25541019

Krantz DS, Burg MM. Current perspective on mental stress-induced myocardial ischemia. Psychosom Med. 2014 Apr;76(3):168-70. doi: 10.1097/PSY.0000000000000054. PMID: 24677165