Joseph T McCabe

B.A., M.S., M.Phil., Ph.D.

Department of Primary Appointment:
School of Medicine
Anatomy, Physiology and Genetics
Title
Professor and Vice Chair for Faculty Affairs, APG
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Traumatic Brain Injury
Behavioral Neuroscience
Office Phone

Education

School Degree Dates

Rutgers College Bachelor of Arts June 1974
New Brunswick, New Jersey

University of Wisconsin Master of Science in December 1976
Oshkosh, Wisconsin Clinical Psychology

City University of New York Master of Philosophy July 1983
New York, New York Doctor of Philosophy in
Neuropsychology

Biography

Dr. Joseph McCabe is Professor and Vice Chair for Faculty Affairs of the Department of Anatomy, Physiology and Genetics, and a Professor in the Neuroscience and the Cell and Molecular Biology Graduate Programs at USU. He received his undergraduate training in psychology and biology at Rutgers College, an M.S. degree in clinical psychology from the University of Wisconsin-Oshkosh, and M.Phil. and Ph.D. degrees from the City University of New York. Dr. McCabe spent 11 years at The Rockefeller University before his move to USU. He serves as the Program Director for Neuroprotection and Modeling of The Center for Neuroscience and Regenerative Medicine. His laboratory is interested in understanding the mechanisms of cell response to stress and in the development of pharmacological therapies that may reduce the functional consequences of brain injury.

Representative publications, projects, and/or deployments

The Rockefeller University Postdoctoral Fellow (1983-July 1985), Research Associate (July 1985-June 1987), Assistant Professor (July 1987-August 1989)

Program Director for Neuroprotection and Modeling, The Center for Neuroscience and Regenerative Medicine, USUHS, 2008-present

Professor of Neuroscience (Secondary) August 1998-present

Professor of Molecular & Cell Biology (Secondary) August 1998-present

First recipient of the University’s, F. Edward Hébert School of Medicine, Outstanding Biomedical Graduate Educator Award, May 16, 1998

USUHS President’s Outstanding Service Medal, May 21, 2012

F. Edward Hébert School of Medicine Impact Award, 2015

Bibliography

McCabe, J.T., Moratz, C., Liu, Y., Egan, R., Chen, H., Liu, J., Budinich, C., Burton, E. E., Danquah, J.K., Myers, M. Animal models for the study of military-related, blast-induced traumatic brain injury. IEEE Xplore, Biomedical Sciences and Engineering Conference (BSEC), 25-26 May 2010, 1–4, Digital Object Identifier: 10.1109/BSEC.2010.5510803, Date of Current Version: 15 July 2010

Budinich, C.S., Chen, H., Lowe, D., Rosenberger, J.G., Bernstock, J.D., McCabe, J.T. Mouse brain PSA-NCAM levels are altered by graded controlled cortical impact injury, Neural Plasticity, 2012, Volume 2012, Article ID 378307, 13 pages, doi:10.1155/2012/378307

Budinich, C.S., Tucker, L.B., Lowe, D., Rosenberger, J.G., McCabe, J.T. Short and long-term motor and behavioral effects of diazoxide and dimethyl sulfoxide administration in the mouse after traumatic brain injury. Pharmacology, Biochemistry & Behavior, 2013, 108, 66-73. DOI information: 10.1016/j.pbb.2013.04.001.

McCabe JT, Moratz C, Liu Y, Burton E, Morgan A, Budinich C, Lowe D, Rosenberger J, Chen H, Liu J, Myers M. High-intensity focused ultrasound (HIFU) exposure as a model for mechanically-induced mild brain injury in mice. Ultrasound in Medicine and Biology, 2014, 40, 965-978.

Guo, H., Liu, J., VanShura, K., Chen, H., Flora, M.N., Myers, T.M., McDonough, J.H., McCabe, J.T. N-Acetyl-aspartyl-glutamate and inhibition of glutamate carboxypeptidases protects against soman-induced neuropathology. NeuroToxicology, 2015, 48, 180-191

Tucker, L.B., Fu, A.H., McCabe, J.T. Performance of male and female C57BL/6J mice on motor and cognitive tasks commonly used in pre-clinical traumatic brain injury research. Journal of Neurotrauma, 2016, 33, 880-894

Tucker, L.B., Burke, J.F., Fu, A.H., McCabe, J.T. Neuropsychiatric symptom modeling in male and female C57BL/6J mice following experimental traumatic brain injury. Journal of Neurotrauma, 2017, 34, 890-905

Tucker, L.B. and McCabe, J.T. Behavior of male and female C57BL/6J mice is more consistent with repeated trials in the elevated zero maze than in the elevated plus maze. Frontiers in Behavioural Neuroscience, 2017, 11 (Article 13) https://doi.org/10.3389/fnbeh.2017.00013

Velosky, A.G., Tucker, L.B., Fu, A.H., Liu, J., McCabe, J.T. Cognitive performance of male and female C57BL/6J mice after repetitive concussive brain injuries. Behavioural Brain Research, 2017, 324, 115-124

Kim, Y., Fu, A., Tucker, L., Liu, J. and McCabe, J.T. Characterization of controlled cortical impact devices by high speed image analysis. Journal of Neuroscience Research, 2018, doi: 10.1002/jnr.24099. [Epub ahead of print]