William H. Catherino

M.D., Ph.D.

Department of Primary Appointment:
School of Medicine
Gynecologic Surgery and Obstetrics
Professor and Chair-Research Division
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Reproductive Endocrinology and Infertility / Obstetrics and Gynecology
Uterine Fibroids
Office Phone


B.S. (Honors): University of Michigan
M.D. (AOA): University of Wisconsin-Madison
Ph.D.: University of Wisconsin-Madison
Residency (OBG): Duke University
Fellowship (REI): National Institutes of Health


Dr. Catherino graduated from the University of Michigan (High Honors and High Distinction) with a Bachelors of Science and the University of Wisconsin-Madison (Alpha Omega Alpha) with M.D. and Ph.D. degrees. He completed his Obstetrics and Gynecology Residency at Duke University Medical Center and his Reproductive Endocrinology and Infertility fellowship at the Combined Federal Fellowship (NIH, WRAMC, NNMC, USUHS). After completing his fellowship, he joined the faculty at the Uniformed Services University of the Health Sciences, while providing patient care at WRNMMC and the NIH. Additionally, he completed additional scholarly training as part of the American Association of Obstetricians and Gynecologists Foundation.

During his 15 years in the Department of Obstetrics and Gynecology at the Uniformed Services University, Dr. Catherino served in a variety of clinical, research, and academic roles including Associate Program Director of the Reproductive Endocrinology and Infertility fellowship, mentor to over 70 scientists at all levels of their training (from high school to post-graduate level), and as a National Faculty Educator for USUHS . He has also played a central role in the Departmental efforts to combine the OBG research resources of WRNMMC and USUHS as part of the Unity of Effort initiative.

Academically, he holds the rank of Professor of Obstetrics and Gynecology with tenure at USU and he has authored or co-authored over 100 peer-reviewed manuscripts. He has numerous teaching accolades, and is sought out to provide unique exposure to the science, medicine, and ethics of his field. While at USUHS, he has record of outstanding service to both the undergraduate, graduate, and post-graduate medical education programs.

Representative publications, projects, and/or deployments

Chair or Presenter, Fibroid Post-Graduate Course, multiple years (ASRM)

Associate Editor, Journal of Assisted Reproduction and Genetics

National Faculty Educator (USUHS)

Ira and Ester Rosenwaks Young Investigator Award (ASRM)

Seminal Article-Fertility and Sterility

Prize Paper Winner (ASRM)

Chair, Committee on Appointments, Promotion and Tenure (USUHS)

Chair, Fibroid Special Interest Group (ASRM)

Oral Boards Examiner and Question Writer for Oral and Written Exam (ABOG)

Inductee-American Gynecologic and Obstetric Society (AGOS)


Lewis TD, Malik M, Britten J, Parikh T, Cox J, Catherino WH. Ulipristal acetate decreases active TGF-beta 3 and its canonical signaling in uterine leiomyoma via two novel mechanisms. Fertil Steril 2019, available electronically (PMID: 30871768)

Britten JL, Malik M, Lewis TD, Catherino WH. Ulipristal acetate mediates decreased proteoglycan expression through regulation of nuclear factor of activated T-cells (NFAT5). Reprod Sci 2019;26:184-97.

Malik M, Britten J, Borahay M, Segars J, Catherino WH. Simvastatin, at clinically relevant concentrations, affects human uterine leiomyoma growth and extracellular matrix production. Fertil Steril 2018;110:1398-407.

Tinelli A, Catherino WH, Gargiulo AR, Hurst BS, Mynbaev OA, Vergara D, Naccarato AG. Uterine fibroids: From molecular oncology to reproduction. Biomed Res Int 2018;2018:6284875.

Lewis TD, Malik M, Britten J, San Pablo AM, Catherino WH. A comprehensive review of the pharmacologic management of uterine leiomyoma. Biomed Res Int 2018;2018:2414609.

Stewart EA, Lytle BL, Thomas L, Wegienka GR, Jacoby V, Diamond MP, Nicholson WK, Anchan RM, Venable S, Wallace K, Marsh EE, Maxwell GL, Borah BJ, Catherino WH, Myers ER. The Comparing Options for Management: PAtient-centered REsults for Uterine Fibroids (COMPARE-UF) registry: rationale and design. Am J Obstet Gynecol 2018;219:95.e1-95.e10.

Cox J, Malik M, Britten J, Lewis T, Catherino WH. Ulipristal acetate and extracellular matrix production in human leiomyomas in vivo: a laboratory analysis of a randomized placebo controlled trial. Reprod Sci 2018;25:198-206.

Stewart EA, Laughlin-Tommaso SK, Catherino WH, Lalitkumar S, Gupta D, Vollenhoven B. Uterine fibroids. Nat Rev Dis Primers 2016;2:16043.

Patel A, Malik M, Britten J, Cox J, Catherino WH. Mifepristone inhibits extracellular matrix formation in uterine leiomyoma. Fertil Steril 2016;105:1102-10.

Protic O, Toti P, Islam MS, Occhini R, Giannubilo SR, Catherino WH, Cinti S, Petraglia F, Ciavattini A, Castellucci M, Hinz B, Ciarmela P. Possible involvement of inflammatory/reparative processes in the development of uterine fibroids. Cell Tissue Res 2016;364:415-27.